- Effects of Long-term Fluoride in Drinking Water on Risks of Hip Fracture of the Elderly: An Ecologic Study Based on Database of Hospitalization Episodes.
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Eun Young Park, Seung Sik Hwang, Jai Yong Kim, Soo Hun Cho
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J Prev Med Public Health. 2008;41(3):147-152.
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DOI: https://doi.org/10.3961/jpmph.2008.41.3.147
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- OBJECTIVES
Fluoridation of drinking water is known to decrease dental caries, particularly in children. However, the effects of fluoridated water on bone over several decades are still in controversy. To assess the risk of hip fracture related to water fluoridation, we evaluated the hip fracture-related hospitalizations of the elderly between a fluoridated city and non-fluoridated cities in Korea. METHODS: Cheongju as a fluoridated area and Chungju, Chuncheon, Suwon, Wonju as non-fluoridated areas were chosen for the study. We established a database of hip fracture hospitalization episode based on the claims data submitted to the Health Insurance Review Agency from January 1995 to December 2002. The hip fracture hospitalization episodes that satisfied the conditions were those that occurred in patients over 65 years old, the injuries had a hip fracture code (ICD-9 820, ICD-10 S72) and the patients were hospitalized for at least 7days. A total of 80,558 cases of hip fracture hospitalization episodes were analyzed. RESULTS: The admission rates for hip fracture increased with the age of the men and women in both a fluoridated city and the non-fluoridated cities (p<0.01). The relative risk of hip fracture increased significantly both for men and women as their age increased. However, any difference in the hip fracture admission rates was not consistently observed between the fluoridated city and the nonfluoridated cities. CONCLUSIONS: We cannot conclude that fluoridation of drinking water increases the risk of hip fracture in the elderly.
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Citations
Citations to this article as recorded by  - The Association between Community Water Fluoridation and Bone Diseases: A Natural Experiment in Cheongju, Korea
Naae Lee, Sungchan Kang, Woojoo Lee, Seung-sik Hwang
International Journal of Environmental Research and Public Health.2020; 17(24): 9170. CrossRef - Community water fluoridation and health outcomes in England: a crossâsectional study
Nicholas Young, John Newton, John Morris, Joan Morris, John Langford, Jonathan Iloya, Diane Edwards, Semina Makhani, Julia Verne
Community Dentistry and Oral Epidemiology.2015; 43(6): 550. CrossRef - Exposure to Fluoride in Drinking Water and Hip Fracture Risk: A Meta-Analysis of Observational Studies
Xin-Hai Yin, Guang-Lei Huang, Du-Ren Lin, Cheng-Cheng Wan, Ya-Dong Wang, Ju-Kun Song, Ping Xu, Yi-Hsiang Hsu
PLOS ONE.2015; 10(5): e0126488. CrossRef - Effects of Life-long Fluoride Intake on Bone Measures of Adolescents
S.M. Levy, J.J. Warren, K. Phipps, E. Letuchy, B. Broffitt, J. Eichenberger-Gilmore, T.L. Burns, G. Kavand, K.F. Janz, J.C. Torner, C.A. Pauley
Journal of Dental Research.2014; 93(4): 353. CrossRef
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